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MicroRNA Mediation of Endothelial Inflammatory Response to Smooth Muscle Cells and its Inhibition by Atheroprotective Shear Stress

RATIONALE: In atherosclerotic lesions, synthetic smooth muscle cells (sSMCs) induce aberrant microRNA (miR) profiles in endothelial cells (ECs) under flow stagnation. Increase in shear stress induces favorable miR modulation to mitigate sSMC-induced inflammation. OBJECTIVE: To address the role of mi...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Chen, Li-Jing, Chuang, Li, Huang, Yi-Hsuan, Zhou, Jing, Lim, Seh Hong, Lee, Chih-I, Lin, Wei-Wen, Lin, Ting-Er, Wang, Wei-Li, Chen, Linyi, Chien, Shu, Chiu, Jeng-Jiann
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380766/
https://ncbi.nlm.nih.gov/pubmed/25623956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.305987
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