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Superagonism at G protein‐coupled receptors and beyond
Ligands targeting GPCRs can be categorized according to their intrinsic efficacy to trigger a specific, receptor‐mediated response. A ligand endowed with the same level of efficacy as the endogenous agonist can be classified as a full agonist, whereas a compound that displays greater efficacy, that...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338155/ https://ncbi.nlm.nih.gov/pubmed/26276510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13278 |
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