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Overexpression of heparanase attenuated TGF‐β‐stimulated signaling in tumor cells
Heparan sulfate (HS) mediates the activity of various growth factors including TGF‐β. Heparanase is an endo‐glucuronidase that specifically cleaves and modifies HS structure. In this study, we examined the effect of heparanase expression on TGF‐β1‐dependent signaling activities. We found that overex...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | FEBS Open Bio |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5337900/ https://ncbi.nlm.nih.gov/pubmed/28286736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12190 |
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