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Bone seeking matrix metalloproteinase-2 inhibitors prevent bone metastatic breast cancer growth

Bone metastasis is common during breast cancer progression. Matrix metalloproteinase-2 (MMP-2) is significantly associated with aggressive breast cancer and poorer overall survival. In bone, tumor or host derived MMP-2 contributes to breast cancer growth and does so by processing substrates includin...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Ther
Main Authors: Tauro, Marilena, Shay, Gemma, Sansil, Samir S., Laghezza, Antonio, Tortorella, Paolo, Neuger, Anthony M., Soliman, Hatem, Lynch, Conor C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337166/
https://ncbi.nlm.nih.gov/pubmed/28069877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0315-T
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