(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone

Matrix Metalloproteinases (MMPs) are a family of secreted and membrane-bound enzymes, of which 24 isoforms are known in humans. These enzymes degrade the proteins of the extracellular matrix and play a role of utmost importance in the physiological remodeling of all tissues. However, certain MMPs, s...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Laghezza, Antonio, Piemontese, Luca, Brunetti, Leonardo, Caradonna, Alessia, Agamennone, Mariangela, Loiodice, Fulvio, Tortorella, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912614/
https://ncbi.nlm.nih.gov/pubmed/33498946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14020085
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