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Osteoclast derived matrix metalloproteinase-9 directly impacts angiogenesis in the prostate tumor-bone microenvironment
In human prostate to bone metastases and in a novel rodent model that recapitulates prostate tumor induced-osteolytic and osteogenic responses, we found that osteoclasts are a major source of the proteinase, MMP-9. Since MMPs are important mediators of tumor-host communication, we tested the impact...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946627/ https://ncbi.nlm.nih.gov/pubmed/20332212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0445 |
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