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Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment

Multiple myeloma is a plasma cell malignancy that homes aberrantly to bone causing extensive skeletal destruction. Despite the development of novel therapeutic agents that have significantly improved overall survival, multiple myeloma remains an incurable disease. Matrix metalloproteinase-2 (MMP-2)...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Shay, Gemma, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo, Sullivan, Daniel M., Hazlehurst, Lori A., Lynch, Conor C.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522031/
https://ncbi.nlm.nih.gov/pubmed/28611279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18103
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