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Compromising KCC2 transporter activity enhances the development of continuous seizure activity
Impaired neuronal inhibition has long been associated with the increased probability of seizure occurrence and heightened seizure severity. Fast synaptic inhibition in the brain is primarily mediated by the type A γ-aminobutyric acid receptors (GABA(A)Rs), ligand-gated ion channels that can mediate...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5337122/ https://ncbi.nlm.nih.gov/pubmed/27108931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.04.029 |
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