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Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities

Alkylation chemotherapy is one of the most widely used systemic therapies for cancer. While somewhat effective, clinical responses and toxicities of these agents are highly variable. A major contributing factor for this variability is the numerous distinct lesions that are created upon alkylation da...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Trends Biochem Sci
Egile Nagusiak: Soll, Jennifer M., Sobol, Robert W., Mosammaparast, Nima
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336464/
https://ncbi.nlm.nih.gov/pubmed/27816326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.10.001
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