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Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities
Alkylation chemotherapy is one of the most widely used systemic therapies for cancer. While somewhat effective, clinical responses and toxicities of these agents are highly variable. A major contributing factor for this variability is the numerous distinct lesions that are created upon alkylation da...
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| Опубликовано в: : | Trends Biochem Sci |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5336464/ https://ncbi.nlm.nih.gov/pubmed/27816326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.10.001 |
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