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Activity and Regulation of Archaeal DNA Alkyltransferase: CONSERVED PROTEIN INVOLVED IN REPAIR OF DNA ALKYLATION DAMAGE

Agents that form methylation adducts in DNA are highly mutagenic and carcinogenic, and organisms have evolved specialized cellular pathways devoted to their repair, including DNA alkyltransferases. These are proteins conserved in eucarya, bacteria and archaea, acting by a unique reaction mechanism,...

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書誌詳細
主要な著者: Perugino, Giuseppe, Vettone, Antonella, Illiano, Giuseppina, Valenti, Anna, Ferrara, Maria C., Rossi, Mosè, Ciaramella, Maria
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281690/
https://ncbi.nlm.nih.gov/pubmed/22167184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308320
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