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Activity and Regulation of Archaeal DNA Alkyltransferase: CONSERVED PROTEIN INVOLVED IN REPAIR OF DNA ALKYLATION DAMAGE
Agents that form methylation adducts in DNA are highly mutagenic and carcinogenic, and organisms have evolved specialized cellular pathways devoted to their repair, including DNA alkyltransferases. These are proteins conserved in eucarya, bacteria and archaea, acting by a unique reaction mechanism,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281690/ https://ncbi.nlm.nih.gov/pubmed/22167184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308320 |
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