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Activity and Regulation of Archaeal DNA Alkyltransferase: CONSERVED PROTEIN INVOLVED IN REPAIR OF DNA ALKYLATION DAMAGE

Agents that form methylation adducts in DNA are highly mutagenic and carcinogenic, and organisms have evolved specialized cellular pathways devoted to their repair, including DNA alkyltransferases. These are proteins conserved in eucarya, bacteria and archaea, acting by a unique reaction mechanism,...

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Detalhes bibliográficos
Main Authors: Perugino, Giuseppe, Vettone, Antonella, Illiano, Giuseppina, Valenti, Anna, Ferrara, Maria C., Rossi, Mosè, Ciaramella, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281690/
https://ncbi.nlm.nih.gov/pubmed/22167184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308320
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