Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival

Pancreatic beta cell failure is the central event leading to diabetes. Beta cells share many phenotypic traits with neurons, and proper beta cell function relies on the activation of several neuron-like transcription programs. Regulation of gene expression by alternative splicing plays a pivotal rol...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Juan-Mateu, Jonàs, Rech, Tatiana H., Villate, Olatz, Lizarraga-Mollinedo, Esther, Wendt, Anna, Turatsinze, Jean-Valery, Brondani, Letícia A., Nardelli, Tarlliza R., Nogueira, Tatiane C., Esguerra, Jonathan L. S., Alvelos, Maria Inês, Marchetti, Piero, Eliasson, Lena, Eizirik, Décio L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336178/
https://ncbi.nlm.nih.gov/pubmed/28077579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748335
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