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SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival
Progressive failure of insulin-producing β-cells is the central event leading to diabetes, but the signaling networks controlling β-cell fate remain poorly understood. Here we show that SRp55, a splicing factor regulated by the diabetes susceptibility gene GLIS3, has a major role in maintaining the...
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| 出版年: | Diabetes |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Diabetes Association
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828453/ https://ncbi.nlm.nih.gov/pubmed/29246973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0736 |
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