MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells

Type 1 diabetes (T1D) is an autoimmune disease leading to β-cell destruction. MicroRNAs (miRNAs) are small noncoding RNAs that control gene expression and organ formation. They participate in the pathogenesis of several autoimmune diseases, but the nature of miRNAs contributing to β-cell death in T1...

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Detalles Bibliográficos
Publicado en:Diabetes
Main Authors: Grieco, Fabio Arturo, Sebastiani, Guido, Juan-Mateu, Jonas, Villate, Olatz, Marroqui, Laura, Ladrière, Laurence, Tugay, Ksenya, Regazzi, Romano, Bugliani, Marco, Marchetti, Piero, Dotta, Francesco, Eizirik, Décio L.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2017
Assuntos:
Islet Studies
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204315/
https://ncbi.nlm.nih.gov/pubmed/27737950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0592
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