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The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition

Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding pathogenesis and thereby to derive...

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Détails bibliographiques
Publié dans:Microbes Infect
Auteurs principaux: Prosser, Gareth, Brandenburg, Julius, Reiling, Norbert, Barry, Clifton Earl, Wilkinson, Robert J., Wilkinson, Katalin A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335906/
https://ncbi.nlm.nih.gov/pubmed/27780773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2016.10.001
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