Mycolates of Mycobacterium tuberculosis modulate the flow of cholesterol for bacillary proliferation in murine macrophages

The differentiation of macrophages into lipid-filled foam cells is a hallmark of the lung granuloma that forms in patients with active tuberculosis (TB). Mycolic acids (MAs), the abundant lipid virulence factors in the cell wall of Mycobacterium tuberculosis (Mtb), can induce this foam phenotype pos...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Lipid Res
Päätekijät: Vermeulen, Ilke, Baird, Mark, Al-Dulayymi, Juma, Smet, Muriel, Verschoor, Jan, Grooten, Johan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Biochemistry and Molecular Biology 2017
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392746/
https://ncbi.nlm.nih.gov/pubmed/28193630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M073171
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