Mycolates of Mycobacterium tuberculosis modulate the flow of cholesterol for bacillary proliferation in murine macrophages

The differentiation of macrophages into lipid-filled foam cells is a hallmark of the lung granuloma that forms in patients with active tuberculosis (TB). Mycolic acids (MAs), the abundant lipid virulence factors in the cell wall of Mycobacterium tuberculosis (Mtb), can induce this foam phenotype pos...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Vermeulen, Ilke, Baird, Mark, Al-Dulayymi, Juma, Smet, Muriel, Verschoor, Jan, Grooten, Johan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392746/
https://ncbi.nlm.nih.gov/pubmed/28193630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M073171
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