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The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition

Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding pathogenesis and thereby to derive...

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Detalhes bibliográficos
Publicado no:Microbes Infect
Main Authors: Prosser, Gareth, Brandenburg, Julius, Reiling, Norbert, Barry, Clifton Earl, Wilkinson, Robert J., Wilkinson, Katalin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335906/
https://ncbi.nlm.nih.gov/pubmed/27780773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2016.10.001
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