Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

Ebola virus (EBOV) causes severe systemic disease in humans and non-human primates characterized by high levels of viremia and virus titers in peripheral organs. The natural portals of virus entry are the mucosal surfaces and the skin where macrophages and dendritic cells (DCs) are primary EBOV targ...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Lüdtke, Anja, Ruibal, Paula, Wozniak, David M., Pallasch, Elisa, Wurr, Stephanie, Bockholt, Sabrina, Gómez-Medina, Sergio, Qiu, Xiangguo, Kobinger, Gary P., Rodríguez, Estefanía, Günther, Stephan, Krasemann, Susanne, Idoyaga, Juliana, Oestereich, Lisa, Muñoz-Fontela, César
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335601/
https://ncbi.nlm.nih.gov/pubmed/28256637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43776
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