Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

Ebola virus (EBOV) causes severe systemic disease in humans and non-human primates characterized by high levels of viremia and virus titers in peripheral organs. The natural portals of virus entry are the mucosal surfaces and the skin where macrophages and dendritic cells (DCs) are primary EBOV targ...

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Vydáno v:Sci Rep
Hlavní autoři: Lüdtke, Anja, Ruibal, Paula, Wozniak, David M., Pallasch, Elisa, Wurr, Stephanie, Bockholt, Sabrina, Gómez-Medina, Sergio, Qiu, Xiangguo, Kobinger, Gary P., Rodríguez, Estefanía, Günther, Stephan, Krasemann, Susanne, Idoyaga, Juliana, Oestereich, Lisa, Muñoz-Fontela, César
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335601/
https://ncbi.nlm.nih.gov/pubmed/28256637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43776
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