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DNA polymerase beta germline variant confers cellular response to cisplatin therapy

Resistance to cancer chemotherapies leads to deadly consequences, yet current research focuses only on the roles of somatically acquired mutations in this resistance. The mutational status of the germline is also likely to play a role in the way cells respond to chemotherapy. The carrier status for...

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Detalles Bibliográficos
Publicado en:Mol Cancer Res
Main Authors: Nemec, Antonia A., Abriola, Laura, Merkel, Jane S., de Stanchina, Elisa, DeVeaux, Michelle, Zelterman, Daniel, Glazer, Peter M., Sweasy, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334281/
https://ncbi.nlm.nih.gov/pubmed/28074003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0227-T
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