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DNA polymerase beta germline variant confers cellular response to cisplatin therapy

Resistance to cancer chemotherapies leads to deadly consequences, yet current research focuses only on the roles of somatically acquired mutations in this resistance. The mutational status of the germline is also likely to play a role in the way cells respond to chemotherapy. The carrier status for...

詳細記述

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Nemec, Antonia A., Abriola, Laura, Merkel, Jane S., de Stanchina, Elisa, DeVeaux, Michelle, Zelterman, Daniel, Glazer, Peter M., Sweasy, Joann B.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334281/
https://ncbi.nlm.nih.gov/pubmed/28074003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0227-T
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