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DNA polymerase beta germline variant confers cellular response to cisplatin therapy

Resistance to cancer chemotherapies leads to deadly consequences, yet current research focuses only on the roles of somatically acquired mutations in this resistance. The mutational status of the germline is also likely to play a role in the way cells respond to chemotherapy. The carrier status for...

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書目詳細資料
發表在:Mol Cancer Res
Main Authors: Nemec, Antonia A., Abriola, Laura, Merkel, Jane S., de Stanchina, Elisa, DeVeaux, Michelle, Zelterman, Daniel, Glazer, Peter M., Sweasy, Joann B.
格式: Artigo
語言:Inglês
出版: 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334281/
https://ncbi.nlm.nih.gov/pubmed/28074003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0227-T
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