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Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer

PURPOSE: The PI3K/Akt signaling axis contributes to the dysregulation of many dominant features in breast cancer including cell proliferation, survival, metabolism, motility and genomic instability. While multiple studies have demonstrated that basal-like or triple negative breast tumors have unifor...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Mehta, Gaurav A., Parker, Joel S., Silva, Grace O., Hoadley, Katherine A., Perou, Charles M., Gatza, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334195/
https://ncbi.nlm.nih.gov/pubmed/28176176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4139-2
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