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Identification of mRNA isoform switching in breast cancer

BACKGROUND: Alternative splicing provides a major mechanism to generate protein diversity. Increasing evidence suggests a link of dysregulation of splicing associated with cancer. While previous genomic-based studies demonstrated the expression of a handful of tumor-specific isoforms, genome-wide al...

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Publicat a:BMC Genomics
Autors principals: Zhao, Wei, Hoadley, Katherine A., Parker, Joel S., Perou, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778320/
https://ncbi.nlm.nih.gov/pubmed/26939613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2521-9
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