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PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration

Here, we identify the LIM protein lipoma-preferred partner (LPP) as a binding partner of a specific protein phosphatase 2A (PP2A) heterotrimer that is characterised by the regulatory PR130/B″α1 subunit (encoded by PPP2R3A). The PR130 subunit interacts with the LIM domains of LPP through a conserved...

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Publicado en:J Cell Sci
Autores principales: Janssens, Veerle, Zwaenepoel, Karen, Rossé, Carine, Petit, Marleen M. R., Goris, Jozef, Parker, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333791/
https://ncbi.nlm.nih.gov/pubmed/26945059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175778
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