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Determination of the pK(a) of the N-terminal amino group of ubiquitin by NMR
Ubiquitination regulates nearly every aspect of cellular life. It is catalysed by a cascade of three enzymes and results in the attachment of the C-terminal carboxylate of ubiquitin to a lysine side chain in the protein substrate. Chain extension occurs via addition of subsequent ubiquitin molecules...
Guardat en:
| Publicat a: | Sci Rep |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333110/ https://ncbi.nlm.nih.gov/pubmed/28252051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43748 |
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