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Determination of the pK(a) of the N-terminal amino group of ubiquitin by NMR

Ubiquitination regulates nearly every aspect of cellular life. It is catalysed by a cascade of three enzymes and results in the attachment of the C-terminal carboxylate of ubiquitin to a lysine side chain in the protein substrate. Chain extension occurs via addition of subsequent ubiquitin molecules...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Oregioni, Alain, Stieglitz, Benjamin, Kelly, Geoffrey, Rittinger, Katrin, Frenkiel, Tom
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333110/
https://ncbi.nlm.nih.gov/pubmed/28252051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43748
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