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NMR Determination of Protein pK(a) Values in the Solid State
Charged residues play an important role in defining key mechanistic features in many biomolecules. Determining the pK(a) values of large, membrane or fibrillar proteins can be challenging with traditional methods. In this study we show how solid-state NMR is used to monitor chemical shift changes du...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885713/ https://ncbi.nlm.nih.gov/pubmed/20563223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz1004413 |
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