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Effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations

INTRODUCTION: The NBN gene product is part of the MRE11/RAD50/NBN complex, which plays an essential role in genomic stability. In the study we try to answer the question what is the effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with homozygous c.657-6...

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Detalhes bibliográficos
Publicado no:Arch Med Sci
Main Authors: Nowak, Jerzy, Świątek-Kościelna, Bogna, Kałużna, Ewelina M., Rembowska, Jolanta, Dzikiewicz-Krawczyk, Agnieszka, Zawada, Mariola, Januszkiewicz-Lewandowska, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332466/
https://ncbi.nlm.nih.gov/pubmed/28261280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2017.65452
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