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Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia

BACKGROUND: The MRE11, RAD50, and NBN genes encode proteins of the MRE11-RAD50-NBN (MRN) complex involved in cellular response to DNA damage and the maintenance of genome stability. In our previous study we showed that the germline p.I171V mutation in NBN may be considered as a risk factor in the de...

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Detalhes bibliográficos
Main Authors: Mosor, Maria, Ziółkowska-Suchanek, Iwona, Nowicka, Karina, Dzikiewicz-Krawczyk, Agnieszka, Januszkiewicz–Lewandowska, Danuta, Nowak, Jerzy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851537/
https://ncbi.nlm.nih.gov/pubmed/24093751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-457
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