Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding

BACKGROUND: MicroRNA dysregulation is a common event in leukemia. Polymorphisms in microRNA-binding sites (miRSNPs) in target genes may alter the strength of microRNA interaction with target transcripts thereby affecting protein levels. In this study we aimed at identifying miRSNPs associated with l...

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Hauptverfasser: Dzikiewicz-Krawczyk, Agnieszka, Macieja, Anna, Mały, Ewa, Januszkiewicz-Lewandowska, Danuta, Mosor, Maria, Fichna, Marta, Strauss, Ewa, Nowak, Jerzy
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059877/
https://ncbi.nlm.nih.gov/pubmed/24886876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-43
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