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Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding

BACKGROUND: MicroRNA dysregulation is a common event in leukemia. Polymorphisms in microRNA-binding sites (miRSNPs) in target genes may alter the strength of microRNA interaction with target transcripts thereby affecting protein levels. In this study we aimed at identifying miRSNPs associated with l...

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Библиографические подробности
Главные авторы:	Dzikiewicz-Krawczyk, Agnieszka, Macieja, Anna, Mały, Ewa, Januszkiewicz-Lewandowska, Danuta, Mosor, Maria, Fichna, Marta, Strauss, Ewa, Nowak, Jerzy
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BioMed Central 2014
Предметы:	Research
Online-ссылка:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4059877/ https://ncbi.nlm.nih.gov/pubmed/24886876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-43
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Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding

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