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Heterozygous p.I171V mutation of the NBN gene as a risk factor for lung cancer development
The NBN gene, also known as NBS1, is located on the chromosome band 8q21.3, and encodes a 754-amino acid-long protein named nibrin. This protein is a member of the MRE1-RAD50-NBN nuclear complex, and is involved in numerous cell processes essential for maintaining genomic stability. Heterozygous var...
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| Publicado no: | Oncol Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665302/ https://ncbi.nlm.nih.gov/pubmed/26722329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3715 |
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