Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages

The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection an...

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Udgivet i:Sci Data
Main Authors: Sun, Jing, Katz, Samuel, Dutta, Bhaskar, Wang, Ze, Fraser, Iain D.C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Data Descriptor
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332009/
https://ncbi.nlm.nih.gov/pubmed/28248930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.7
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