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Genome-wide siRNA screen of genes regulating the LPS-induced TNF-α response in human macrophages
The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection an...
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| Опубликовано в: : | Sci Data |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5332009/ https://ncbi.nlm.nih.gov/pubmed/28248930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.7 |
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