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Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links
DNA interstrand cross-links (ICLs) block replication fork progression by inhibiting DNA strand separation. Repair of ICLs requires sequential incisions, translesion DNA synthesis, and homologous recombination, but the full set of factors involved in these transactions remains unknown. We devised a t...
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| Veröffentlicht in: | Science |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331883/ https://ncbi.nlm.nih.gov/pubmed/25931565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253671 |
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