Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

DNA interstrand cross-links (ICLs) block replication fork progression by inhibiting DNA strand separation. Repair of ICLs requires sequential incisions, translesion DNA synthesis, and homologous recombination, but the full set of factors involved in these transactions remains unknown. We devised a t...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Räschle, Markus, Smeenk, Godelieve, Hansen, Rebecca K., Temu, Tikira, Oka, Yasuyoshi, Hein, Marco Y., Nagaraj, Nagarjuna, Long, David T., Walter, Johannes C., Hofmann, Kay, Storchova, Zuzana, Cox, Jürgen, Bekker-Jensen, Simon, Mailand, Niels, Mann, Matthias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331883/
https://ncbi.nlm.nih.gov/pubmed/25931565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253671
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