Melanin or a Melanin-Like Substance Interacts with the N-Terminal Portion of Prion Protein and Inhibits Abnormal Prion Protein Formation in Prion-Infected Cells

Prion diseases are progressive fatal neurodegenerative illnesses caused by the accumulation of transmissible abnormal prion protein (PrP). To find treatments for prion diseases, we searched for substances from natural resources that inhibit abnormal PrP formation in prion-infected cells. We found th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Hamanaka, Taichi, Nishizawa, Keiko, Sakasegawa, Yuji, Oguma, Ayumi, Teruya, Kenta, Kurahashi, Hiroshi, Hara, Hideyuki, Sakaguchi, Suehiro, Doh-ura, Katsumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Prions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331829/
https://ncbi.nlm.nih.gov/pubmed/28077650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01862-16
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge