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Efficacy and Mechanism of a Glycoside Compound Inhibiting Abnormal Prion Protein Formation in Prion-Infected Cells: Implications of Interferon and Phosphodiesterase 4D-Interacting Protein

A new type of antiprion compound, Gly-9, was found to inhibit abnormal prion protein formation in prion-infected neuroblastoma cells, in a prion strain-independent manner, when the cells were treated for more than 1 day. It reduced the intracellular prion protein level and significantly modified mRN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nishizawa, Keiko, Oguma, Ayumi, Kawata, Maki, Sakasegawa, Yuji, Teruya, Kenta, Doh-ura, Katsumi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993762/
https://ncbi.nlm.nih.gov/pubmed/24453367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03775-13
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