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Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases

Heparan sulfate (HS) is a sulfated polysaccharide exhibiting essential physiological functions. HS 6-O-sulfotransferase (6-OST) transfers a sulfo group to the 6-OH position of glucosamine units to confer a variety of HS biological activities. There are three different isoforms of 6-OST in the human...

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Foilsithe in:ACS Chem Biol
Main Authors: Xu, Yongmei, Moon, Andrea F, Xu, Shuqin, Krahn, Juno M., Liu, Jian, Pedersen, Lars C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331487/
https://ncbi.nlm.nih.gov/pubmed/28103688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00841
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