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Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases
Heparan sulfate (HS) is a sulfated polysaccharide exhibiting essential physiological functions. HS 6-O-sulfotransferase (6-OST) transfers a sulfo group to the 6-OH position of glucosamine units to confer a variety of HS biological activities. There are three different isoforms of 6-OST in the human...
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Publicado no: | ACS Chem Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331487/ https://ncbi.nlm.nih.gov/pubmed/28103688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00841 |
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