Combined Ligand/Structure-Based Virtual Screening and Molecular Dynamics Simulations of Steroidal Androgen Receptor Antagonists

The antiandrogens, such as bicalutamide, targeting the androgen receptor (AR), are the main endocrine therapies for prostate cancer (PCa). But as drug resistance to antiandrogens emerges in advanced PCa, there presents a high medical need for exploitation of novel AR antagonists. In this work, the r...

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Detaylı Bibliyografya
Yayımlandı:Biomed Res Int
Asıl Yazarlar: Wang, Yuwei, Han, Rui, Zhang, Huimin, Liu, Hongli, Li, Jiazhong, Liu, Huanxiang, Gramatica, Paola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331419/
https://ncbi.nlm.nih.gov/pubmed/28293633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3572394
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