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Structure-based Virtual Screening and Identification of a Novel Androgen Receptor Antagonist
Hormonal therapies, mainly combinations of anti-androgens and androgen deprivation, have been the mainstay treatment for advanced prostate cancer because the androgen-androgen receptor (AR) system plays a pivotal role in the development and progression of prostate cancers. However, the emergence of...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436320/ https://ncbi.nlm.nih.gov/pubmed/22798067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379107 |
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