Structure-based Virtual Screening and Identification of a Novel Androgen Receptor Antagonist

Hormonal therapies, mainly combinations of anti-androgens and androgen deprivation, have been the mainstay treatment for advanced prostate cancer because the androgen-androgen receptor (AR) system plays a pivotal role in the development and progression of prostate cancers. However, the emergence of...

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Hlavní autoři: Song, Chin-Hee, Yang, Su Hui, Park, Eunsook, Cho, Suk Hee, Gong, Eun-Yeung, Khadka, Daulat Bikram, Cho, Won-Jea, Lee, Keesook
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436320/
https://ncbi.nlm.nih.gov/pubmed/22798067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379107
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