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Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
Mechanistic target of rapamycin (mTOR) coordinates biosynthetic and catabolic processes in response to multiple extracellular and intracellular signals including growth factors and nutrients. This serine/threonine kinase has long been known as a critical regulator of muscle mass. The recent finding...
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| Published in: | EMBO Mol Med |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331267/ https://ncbi.nlm.nih.gov/pubmed/28130275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606547 |
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