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Therapeutic Benefit of Autophagy Modulation in Pompe Disease

The complexity of the pathogenic cascade in lysosomal storage disorders suggests that combination therapy will be needed to target various aspects of pathogenesis. The standard of care for Pompe disease (glycogen storage disease type II), a deficiency of lysosomal acid alpha glucosidase, is enzyme r...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Lim, Jeong-A, Sun, Baodong, Puertollano, Rosa, Raben, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035739/
https://ncbi.nlm.nih.gov/pubmed/29804932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.025
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