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RNA Primer Extension Hinders DNA Synthesis by Escherichia coli Mutagenic DNA Polymerase IV

In Escherichia coli the highly conserved DNA damage regulated dinB gene encodes DNA Polymerase IV (DinB), an error prone specialized DNA polymerase with a central role in stress-induced mutagenesis. Since DinB is the DNA polymerase with the highest intracellular concentrations upon induction of the...

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Publicat a:Front Microbiol
Autors principals: Tashjian, Tommy F., Lin, Ida, Belt, Verena, Cafarelli, Tiziana M., Godoy, Veronica G.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331060/
https://ncbi.nlm.nih.gov/pubmed/28298904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00288
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