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RNA Primer Extension Hinders DNA Synthesis by Escherichia coli Mutagenic DNA Polymerase IV

In Escherichia coli the highly conserved DNA damage regulated dinB gene encodes DNA Polymerase IV (DinB), an error prone specialized DNA polymerase with a central role in stress-induced mutagenesis. Since DinB is the DNA polymerase with the highest intracellular concentrations upon induction of the...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Tashjian, Tommy F., Lin, Ida, Belt, Verena, Cafarelli, Tiziana M., Godoy, Veronica G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331060/
https://ncbi.nlm.nih.gov/pubmed/28298904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00288
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