BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis

BACKGROUND: CD4(+) T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T helper 17 (Th17) cells are indispensable for clearance of intracellular as wel...

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Detalhes bibliográficos
Publicado no:Biol Res
Main Authors: Kang, Youra, Timilshina, Maheshwor, Nam, Tae-gyu, Jeong, Byeong-Seon, Chang, Jae-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330010/
https://ncbi.nlm.nih.gov/pubmed/28241881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-017-0113-z
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