BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway

5-Hydroxytryptamine (5-HT) induces proliferation of cancer cells and vascular cells. In addition to 5-HT production by several cancer cells including gastrointestinal and breast cancer, a significant level of 5-HT is released from activated platelets in the thrombotic environment of tumors, suggesti...

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Veröffentlicht in:PLoS One
Hauptverfasser: Banskota, Suhrid, Gautam, Jaya, Regmi, Sushil C., Gurung, Pallavi, Park, Myo-Hyeon, Kim, Seung Joo, Nam, Tae-gyu, Jeong, Byeong-Seon, Kim, Jung-Ae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732985/
https://ncbi.nlm.nih.gov/pubmed/26824764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148133
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