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Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation in the gastrointestinal tract. Biological therapeutics and orally available small molecules like tofacitinib (a JAK inhibitor) have been developed to treat IBD, but half of the patients treated with these drugs fail to achieve sust...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Gurung, Pallavi, Dahal, Sadan, Chaudhary, Prakash, Guragain, Diwakar, Karmacharya, Ujjwala, Kim, Jung-Ae, Jeong, Byeong-Seon
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247564/
https://ncbi.nlm.nih.gov/pubmed/32365634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093145
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