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Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation in the gastrointestinal tract. Biological therapeutics and orally available small molecules like tofacitinib (a JAK inhibitor) have been developed to treat IBD, but half of the patients treated with these drugs fail to achieve sust...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Gurung, Pallavi, Dahal, Sadan, Chaudhary, Prakash, Guragain, Diwakar, Karmacharya, Ujjwala, Kim, Jung-Ae, Jeong, Byeong-Seon
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247564/
https://ncbi.nlm.nih.gov/pubmed/32365634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093145
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