BJ-3105, a 6-Alkoxypyridin-3-ol Analog, Impairs T Cell Differentiation and Prevents Experimental Autoimmune Encephalomyelitis Disease Progression

CD4(+) T cells are essential in inflammation and autoimmune diseases. Interferon-γ (IFN-γ) secreting T helper (Th1) and IL-17 secreting T helper (Th17) cells are critical for several autoimmune diseases. To assess the inhibitory effect of a given compound on autoimmune disease, we screened many comp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Timilshina, Maheshwor, Kang, Youra, Dahal, Ishmit, You, Zhiwei, Nam, Tae-gyu, Kim, Keuk-Jun, Jeong, Byeong-Seon, Chang, Jae-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241145/
https://ncbi.nlm.nih.gov/pubmed/28095433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168942
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